WashU Mass Spectrometry

Mass Spectrometry Technology Access Center 

at the McDonnell Genome Institute -

Washington University School of Medicine

The Mass Spectrometry Technology Access Center at the McDonnell Genome Institute MTAC@MGI - Washington University School of Medicine offers cutting-edge proteomics, metabolomics, lipidomics, and imaging mass spectrometry technologies to support and educate researchers worldwide in answering current questions in basic, translational, and clinical research.

At MTAC, we are dedicated to delivering top-notch mass spectrometry-based research that is both cost-effective and efficient. We offer a complimentary initial consultation to review each project and provide ongoing support for successful outcomes.

Our services range from simple protein identification to quantification of proteins (relative and absolute) through bottom-up proteomics analyses. We also offer intact, native, and top-down proteomics analyses. Our specialty lies in providing comprehensive global quantitative analysis of post-translational modifications (PTMs) such as phosphorylation, ubiquitination, acetylation, and methylation, as well as epiproteomics histone PTM assays.

In addition, we continuously develop new targeted metabolomics and lipidomics panels, and we fully support spatial proteome and metabolome imaging mass spectrometry. From sample submission to data analysis, we offer comprehensive services with the support of our world-class staff and state-of-the-art mass spectrometry instrumentation.

The MTAC provides advanced mass spectrometry analyses to the Washington University community and beyond.

Our Mission

Submit your samples for a specific task, using our established and validated protocols and services. Our fees are based on a cost-study approved rate, charged per sample.

Partial Funded Staff, Grant Collaborator

Partner with us through partial funding of an MTAC staff member or postdoctoral associate. We'll assign a dedicated mass spectrometry specialist to your project.

Full Funded Staff, Grant Co-Investigator

Join forces on a research grant and work towards a specific aim. This option is best for large commitments that require the development of new applications or the adaptation of cutting-edge technology.

Pilot Study 

New to mass spectrometry-based "omics"? Get a taste of what we can do by taking advantage of our free analysis set after an initial consultation.


Work performed by the MTAC should be acknowledged as shown below:

" Mass Spectrometry analyses were performed by the Mass Spectrometry Technology Access Center at the McDonnell Genome Institute (MTAC@MGI) at Washington University School of Medicine, supported by the Diabetes Research Center/NIH grant P30 DK020579, Institute of Clinical and Translational Sciences/NCATS CTSA award UL1 TR002345, and Siteman Cancer Center/NCI CCSG grant P30 CA091842."

Contact MassSpec@wustl.edu to get more information

Request a Project Consultation

Initiate a new project, start a new collaboration, or request a services consultation to discuss your mass spectrometry needs.

Download a Form

Choose your service and download the corresponding PDF form for completion.

Submit a Sample

Notify us of your sample submission by uploading the completed PDF form or sending it via email to MassSpec@wustl.edu. If you have any questions or inquiries, please let us know.

*Please note that uploading the PDF form requires a Google Drive sign-in, but MTAC does NOT collect, sell, or share your Google sign-in information. An email submission to MassSpec@wustl.edu is also an option.

McDonnell Genome Institute

Genome Technology Access Center @ MGI

Functional Imaging for Variant Elucidation

Genome Editing and iPSC Center @ MGI