Imaging Services
Spatially resolved MALDI mass spectrometric imaging of human brain tissue for metabolites, lipids, and peptides. Link
MTAC's multi-omics by MSI:
-Spatial Metabolomics
-Spatial Lipidomics
-Spatial Glycomics
-Spatial Peptidomics
-Spatial Proteomics
Spatial Multi-Omics by Mass Spectrometry Imaging (MSI)
Imaging mass Spectrometry has proven immense value in studying molecular distributions in tissue sections in a variety of application areas, ranging from clinical research to environmental sciences, and the pharmaceutical industry. MTAC has developed a robust workflow to facilitate Spatial Multi-Omics through Mass Spectrometry Imaging (MSI). This comprehensive approach allows for the visualization of analytes such as metabolites, lipids, peptides, proteins, and glycans in various tissues, including those from human, mouse, rat, ant, and zebrafish. Compatible with fresh-frozen, FFPE, and Davidson’s fixative paraffin-embedded (DFPE) tissues, MTAC enables high-quality imaging across diverse anatomical structures, including the brain, kidney, liver, spleen, pancreas, lung, intestine, knee joint, larynx, and muscle tissues.
Pricing
WashU: Contact us for a quote
External Academic/Nonprofit: Contact us for a quote
External For-Profit Industry: Contact us for a quote
Instruments Used
MTAC's MALDI-Guided-LCM Applicaitons:
-Spatial Proteomics
-Spatial Metabolomics
-Spatial Lipidomics
Spatial Multi-Omics by MALDI-LCM-MS/MS
MTAC has established a cutting-edge application, MALDI-MSI-guided LCM-MS, combining mass spectrometry imaging and laser capture microdissection (LCM). Our approach enables comprehensive profiling and quantitative analysis of proteome, metabolome, and lipidome, providing new insights into complex biological systems and molecular distribution.
Pricing
WashU: Contact us for a quote
External Academic/Nonprofit: Contact us for a quote
External For-Profit Industry: Contact us for a quote
Instruments Used
Acknowledgement
Work performed by the MTAC should be acknowledged as shown below:
"Mass Spectrometry analyses were performed by the Mass Spectrometry Technology Access Center at the McDonnell Genome Institute (MTAC@MGI) at Washington University School of Medicine, supported by the Diabetes Research Center/NIH grant P30 DK020579, Institute of Clinical and Translational Sciences/NCATS CTSA award UL1 TR002345, and Siteman Cancer Center/NCI CCSG grant P30 CA091842."
Contact MassSpec@wustl.edu to get more information
Ask for a Project Consultation
Initiate a new project, start a new collaboration or request a services consultation to discuss your Mass Spectrometry needs.
Download Form
Select your service. Download the service PDF form and complete.
Submit a Sample
Notify us of your sample submission by uploading your PDF form or email the form to us. Let us know if you have any inquiries.
*PDF upload requires Google Drive sign-in however MTAC does NOT collect, sell, or share your Google sign-in information. Alternatively, PDFs can be submitted to MassSpec@wustl.edu
